was successfully added to your cart.

Side Effects of Tadalafil (Adcirca, Cialis)

FIND A PHARMACIST WHO OFFERS GENETIC TESTING FOR PDE5 Inhibitors

Side Effects of Tadalafil (Cialis)

Tadalafil, available as the brand Cialis, is a PDE5 (phosphodiesterase 5) inhibitor. It is primarily used for the treatment of erectile dysfunction.

Serious Side Effects

Severe side effects of Cialis are:

 

  • Chest tightness or heaviness
  • Chills
  • Cold sweats
  • Confusion
  • Dizziness
  • Fainting
  • Fast or irregular heartbeat
  • Headache
  • Hearing loss
  • Nausea
  • Nervousness
  • Pain or discomfort in the arms, jaw, back, or neck
  • Pounding in the ears
  • Shortness of breath
  • Priapism (prolonged and painful erection not caused by sexual stimulation)
  • Sudden hearing loss

 

(Cialis label reported by the FDA).

Common Side Effects

The Cialis drug label listed by the FDA, also outlines the common side effects: indigestion, stomach discomfort or pain, belching, and heartburn.

Less Common Side Effects

According to the FDA, the rare side effects of Cialis are congestion, difficulty with moving, difficulty with swallowing, bloody nose, body aches or pain,burning, dry, or itching eyes, dry mouth, eye pain, feeling of constant movement of self or surroundings,flushing, excessive eye discharge, fever, hoarseness, and increased erection.

About Pharmacogenetic Testing

Some patients do not develop adverse effects when taking Cialis, while others suffer negative reactions. This inter variability might be explained by differences in the genetics between individuals. Individual gene variants called “polymorphisms” encode for a family of liver enzymes that metabolize Cialis. This may increase or decrease a patient’s chances of developing side effects, depending on the patient’s genetically determined ability to break down and process the drug.

 

Slow metabolizers have an inefficient liver enzyme variant that does not break down the drug, As a result, slow metabolizers are at higher risk of suffering from toxicity or adverse reactions. In contrast, fast metabolizers have a liver enzyme variant that allows them to efficiently process the drug. Fast metabolizers will most likely require a higher dose of that drug in order to receive the benefits of the medication. Knowing a patient’s pharmacogenetic results enables prescribers to find a safe and effective dose and importantly, before treatment begins.

Understand Your Risk with the Rxight® Genetic Test

MD Labs’ Rxight® pharmacogenetic testing service analyzes your genetically modulated response. Rxight® just requires a DNA cheek swab test at a participating pharmacy that offers the test. The sample is then sent to our lab where 18 genes and their alleles are analyzed.

 

This establishes how a patient is likely to react to Cialis and hundreds of other commonly used prescriptions. The results can then be used to guide clinical decision-making on the appropriate dose, unlike the traditional “trial-and-error” approach that prescribers still use saving you time and money and most importantly, preventing severe side effects from occurring.

 

Still have more questions on Rxight®? Give us a call at 1-888-888-1932 or an email at support@Rxight.com for more information.

 

Contributors to this Article:
Michael Sapko, MD, PhD; and Deborah Kallick, PhD, Medicinal Chemistry

Read more about Rxight® Drug Sensitivity Testing