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Side Effects of Darifenacin (Enablex)


Side Effects of Darifenacin (Enablex)

Darifenacin, available as the Enablex, is a prescription medicine that blocks a specific neurotransmitter. It is used for the treatment of overactive bladder with symptoms of urinary frequency and incontinence. Enablex works by relaxing the muscles in the bladder improving the ability to control urination. It helps to reduce the leaking of urine, feelings of needing to urinate immediately, and frequent trips to the bathroom. This medication belongs to a class of drugs called antispasmodics.

Serious Side Effects

The FDA lists the adverse drug effects that may happen when taking Enablex. They include:


  • Constipation
  • Dry mouth
  • Abnormal vision
  • Hot and dry skin
  • Extreme thirst
  • Hallucinations
  • Constipation
  • Pain or burning when you urinate
  • Confusion
  • Severe stomach pain
  • Severe skin reaction
  • Swelling in your face, tongue, or throat
  • Sore throat
  • Burning in your eyes
  • Fever


Get emergency help if you have any of signs of an allergic reaction, such as hives or difficulty in breathing. Contact a doctor immediately if you have any of these serious side effects.

About Pharmacogenetic Testing

Aside from the common and adverse drug reactions already discussed, there is a subset of patients who are poor metabolizers of Enablex. That information could be used to alter the dose of Enablex, creating an extra layer of safety when taking the medication.

Understand Your Risks with the Rxight® Genetic Test

The Rxight® test is the result of the growing field of pharmacogenetics in which individual gene variations in the population are researched and compared against the medication for understanding on how you will react to the drug. Your results from the Rxight® test will inform you, your pharmacist and your provider on what drugs you can take safely and what medicines you may have trouble metabolizing. Instead of gathering this information by trial and error, your provider could have this data from these results.



Contributors to this Article:
Michael Sapko, MD, PhD; and Deborah Kallick, PhD, Medicinal Chemistry

Read more about Rxight® Individualized Medicine