Side Effects of Felbamate (Felbatol)
Felbamate, available under the brand Felbatol, is the first anticonvulsant drug with dual actions on excitatory (NMDA) and inhibitory (GABA) brain mechanisms. It is used to treat partial seizures in adults and partial and generalized seizures associated with Lennox–Gastaut syndrome in children. Fatal aplastic anemia (the body stops producing new blood cells) and liver failure limits Felbatol from treating severe refractory epilepsy. Ordinarily, a patient should not be placed on and or continued on Felbatol without consideration of an appropriate expert hematologic consultation.
An epilepsy diagnosis can be confusing as there are a number of types of epilepsy. Be sure to talk to your physician to understand what type of epilepsy you have and what drugs are preferred for your condition. Tell your doctor about your medical condition and about every drug and over-the-counter product you are taking for the safest treatment.
Common Side Effects
The FDA outlines the common side effects of Felbatol:
- Decreased appetite
Two rare but very serious effects include aplastic anemia and hepatic (liver) failure. There are many less serious side effects that may go away with continued use (Felbatol label reported by the FDA).
About Pharmacogenetic Testing
One way to potentially lessen side effects is to ask your physician about the pharmacogenetics test Rxight from MD Labs. Medically important pharmacogenetics research emerged from the sequencing of the human genome. This research shows that individuals have wide variation in their genes that process (metabolize) most drugs on the market. A number of genes encode the enzymes that actually process (metabolize) the drugs you take.
Know Your Risk with the Rxight® Genetic Test
The Rxight® test provides you and your physician with a comprehensive analysis of your relevant genes. With these results in your Rxight® report, your physician will be allowed to safely prescribe over 200 drugs on the market and over-the-counter (OTC) products. All that is required is a simple cheek swab at your participating pharmacy. Ask your physician today about the RxightTM pharmacogenetics test.
Contributors to this Article:
Michael Sapko, MD, PhD; and Deborah Kallick, PhD, Medicinal Chemistry
Read more about Rxight® Genetic Testing Labs