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Side Effects of Gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)


Description: Neurontin (generic name: gabapentin) is an anticonvulsant, also known as an anti-epileptic, or anti-seizure medication. It is approved for the treatment of focal seizures, partial seizures and mixed seizures. It also affects nerves and chemicals in the body that are involved in some types of pain, and so is also used to treat nerve pain caused by shingles, herpes virus or diabetic neuropathy. Off-label uses are for anxiety disorders, insomnia, and bipolar disorder.

Serious Side Effects of Neurontin

According to the Neurontin medication guidelines as reported by the U.S. Food and Drug Administration (Sep 2015), some side effects are severe and require emergency treatment. These include: severe weakness or tiredness, upper stomach pain, severe tingling or numbness, increased seizures, rapid back and forth movement of your eyes, kidney problems, severe skin reactions (including the potentially fatal Stevens-Johnson Syndrome), chest pain and new or worsening cough with fever or trouble breathing.


Other severe reactions that were updated by the FDA in 2013 as reported in the Neurotonin Drug Safety Guidelines include: increase in blood creatine phosphokinase (CPK) levels and rhabdomyolysis (destruction of a type of muscle cell); high CPK can be toxic and dangerous to your heart and other muscles; central nervous system and suicide ideation.

Common Side Effects of Neurontin

According to the Neurontin drug label as reported by the FDA, common side effects include:

  • Unsteady gait
  • Drowsiness
  • Weight gain
  • Swelling of hands, legs or feet
  • Loss of coordination
  • Dizziness
  • Weight gain
  • Ataxia
  • Abnormal thinking
  • Dry mouth
  • Flatulence
  • Infection
  • Less Common Side Effects Neurontin

    According to the Neurontin drug label as reported by the FDA, less common adverse reactions to Neurontin/gabapentin include:

  • Amnesia
  • Blurred or double vision
  • Dyspepsia
  • Dyspnea
  • Impotence
  • Flu syndrome
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    Contributors to this Article: Michael Sapko, MD, Phd and Deborah Kallick, PhD, Medicinal Chemistry

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